SMAD3 Inhibtor, SIS 3

Basic information

Name

SMAD3 Inhibtor, SIS 3

size

2,5 mg

Catalog number

S564500

Price

231 €

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Extended information

Chemical's molecular weight

453.53

Chemical's formula

C28H27N3O3

Cas number

1009104-85-1

Stock availability

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Storage

No Data Available

Stability conditions

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Chemical's soluble in

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Boiling temperature

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Melting temperature

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Physical properties

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Chemical available in other sizes

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Chemical's category

Amines, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals

Other name

1-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-propen-1-one

Chemical's main applications

SMAD3 Inhibitor, SIS3 selectively inhibits TGF-β and activin. It has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts.