Smad2 (7A5) Monoclonal Antibody
0.1ml
bsm-50316M
362 €
7A5
4087
None
Smad2
Q15796
WB, IP
anticorps
Monoclonal
1ug per 1ul
Unconjugated
Human, Mouse, Rat
Primary Antibodies
Unmodified antibody
Purified by Protein G.
WB (0.1 ug/mL) IP (2.0 ug)
Smad2 (7A5) Monoclonal Antibody
Smad2 (7A5) Monoclonal Antibody
This is a highly specific antibody against Smad2.
Recombinant human protein purified from E.coli (His-Smad2)
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2; Mothers against decapentaplegic homolog 2; MAD homolog 2; Mothers against DPP homolog 2; Mad-related protein 2; SMAD family member 2; SMAD 2; Smad2
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
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