anti-Smad3 (phospho Ser425) Antibody

Basic information

Name

anti-Smad3 (phospho Ser425) Antibody

size

0.1 mg

Catalog number

79-237

Price

180 €

Details & buy    

Extended information

NCBI GENE nr

4088

GENE symbol

SMAD3

Ab raised in

Rabbit

KDa

52 kDa

Protein nr

P84022

Quantity per ml

1 mg/mL

French translation

anticorps

Omim nr

223029440

Type

Polyclonal

Vial with antibody

in solution

Source

Homo sapiens

Ncbi nr

NP_001138574.1

Antibodie's label

unlabelled serum

Works with

Human, Mouse, Rat

Antigene name

SMAD family member 3

Immuno application

immuno-histo-chemistry

Antibody advice

, Immunohistochemistry: 1:50~1:100

Keep at

Store antibody at -20 grades C for up to one year.

Spicific to

This antibody detects endogenous level of Smad3 only when phosphorylated at serine 425.

Gene names

LDS3, LDS1C, MADH3, JV15-2, HSPC193, HsT17436, PTP2C, SHPTP2, MAD-3, Mad3, Mothers against DPP homolog 3

Suspention, pH, azide

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Properties

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Antigen

Smad3 (Phospho-Ser425) antibody was made against a peptide sequence around phosphorylation site of serine 425 (C-S-S-V-S (p) ) derived from Human Smad3.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Purity

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Gene info

Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.