SMURF1 Polyclonal Antibody

Basic information

Name

SMURF1 Polyclonal Antibody

size

50 μg

Catalog number

CAC07256

Price

245 €

Extended information

Raised in

Rabbit

Use before

1 year

Protein number

Q9HCE7

Shipping requirements

Blue ice

French translation

anticorps

Clonality

Polyclonal

Verified reactivity

Human, Mouse

Estimated production time

3-7 business days

NCBI number

Please refer to NCBI

Gene number

Please refer to GenBank

Purity

Protein G purified,>95%

Group

Polyclonals and antibodies

Notes

For research use only. Not for diagnostic procedures.

Storage recommendation

Aliquot and store at -20°C. Minimize freezing and thawing.

Immunogen

Recombinant human E3 ubiquitin-protein ligase SMURF1 protein (198-374AA)

Verified applications

ELISA,WB,IHC,IF. Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IF:1:50-1:200

Properties

If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Other name

E3 ubiquitin-protein ligase SMURF1,SMAD ubiquitination regulatory factor 1,SMAD-specific E3 ubiquitin-protein ligase 1,SMURF1,KIAA1625

About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

Supplementary information

E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Plays a role in dendrite formation by melanocytes (PubMed:23999003).