Rabbit Anti Human SMAD1 Antibody-Biotin

Basic information

Name

Rabbit Anti Human SMAD1 Antibody-Biotin

size

50ug

Catalog number

CSB-PA618998LD01HU_50ug

Price

212 €

Extended information

Antibody isotype

IgG

Purity

>95%

Species reactivity

Human

Tested applications & recommended dilutions

ELISA

Immunogen species

Human

Conjugation

Biotin

UniProt ID

Q15797

French translation

anticorps

Additional conjugation

Biotinylated

Purification method

Protein G purified

Clonality

Polyclonal antibody

Synonym name

SMAD1 Human Antibody

Latin name

Oryctolagus cuniculus

Antibody category

Polyclonal Antibodies

Format

Liquid, diluted in buffer

Long name

Rabbit Antibody against Human SMAD1, Biotin

Buffer composition

Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Immunogen type

Recombinant human Mothers against decapentaplegic homolog 1 protein (202-335AA)

Alias

Mothers against decapentaplegic homolog 1,MAD homolog 1,Mothers against DPP homolog 1,SMAD1,BSP1,MADH1,MADR1,JV4-1,Mad-related protein 1,SMAD family member 1,SMAD 1,Smad1,hSMAD1,Transforming growth factor-beta-signaling protein 1,BSP-1

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.

Shipping and storage

SMAD1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.

Background

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.

About

Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.

Properties

If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.