Smad1 + Smad5 Antibody, ALEXA FLUOR 488

Basic information

Name

Smad1 + Smad5 Antibody, ALEXA FLUOR 488

size

100ul

Catalog number

bs-1619R-A488

Price

380 €

Extended information

Modification Site

None

Crossreactivity

Human

French translation

anticorps

Tested applications

IF(IHC-P)

Clonality

Polyclonal

Gene ID Number

4090, 4086

Modification

Unmodified

Excitation emission

499nm/519nm

Immunogen range

405-440/465

Concentration

1ug per 1ul

Conjugation

Alexa Fluor

Target Antigen

Smad1 + Smad5

Conjugated with

ALEXA FLUOR® 488

Subcellular location

Cytoplasm, Nucleus

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-Smad1 + Smad5 PAb ALEXA FLUOR 488

Specificity

This is a highly specific antibody against Smad1 + Smad5.

Long name

Smad1 + Smad5 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Synonyms

Mothers against decapentaplegic homolog 5; SMAD5; Mothers against decapentaplegic homolog 1; SMAD1

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Smad 5

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Background of the antigen

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Smad1 + Smad5 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.