Smad1 + Smad5
ALEXA FLUOR® 488
Purified by Protein A.
Conjugated Primary Antibodies
Rabbit (Oryctolagus cuniculus)
Also known as
Anti-Smad1 + Smad5 PAb ALEXA FLUOR 488
This is a highly specific antibody against Smad1 + Smad5.
Smad1 + Smad5 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
Cross-reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Mothers against decapentaplegic homolog 5; SMAD5; Mothers against decapentaplegic homolog 1; SMAD1
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Smad 5
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Background of the antigen
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Smad1 + Smad5 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.