Name: Smad3 Antibody
SKU: 01012615894
Price: 374 EUR
Availability: InStock

Basic information

Name

Smad3 Antibody

size

0,1 mg

Catalog number

PB9396

Price

374 €

Details & buy

Extended information

Analyses

Entrez GeneID

4088

Target antigen

Smad3

Reacts with species:

human

Gene Name

SMAD3

Raised in

rabbit

Uniprot ID

P84022

French translation

anticorps

Product form

freeze-dried

Clonality

Polyclonal antibody

Clone

Polyclonal antibody

Gene Full Name

SMAD family member 3

Type of the antibody

IgG polyclonal antibody

Purification

Immunogen affinity purified.

Protein Name

Mothers against decapentaplegic homolog 3

Product configuration

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Solubilization

The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml

Properties

If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Smad3 (193-222aa DHQMNHSMDAGSPNLSPNPMSPAHNNLDLQ), identical to the related mouse and rat sequences.

Tips

The Smad3 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.

1. "Entrez Gene: SMAD3 SMAD family member 3". 2. Moustakas A, Souchelnytskyi S, Heldin CH (2001). "Smad regulation in TGF-beta signal transduction". J. Cell. Sci. 114 (Pt 24): 4359–69. 3. Zhang Y, Feng X, We R, Derynck R (September 1996). "Receptor-associated Mad homologues synergize as effectors of the TGF-beta response". Nature 383 (6596): 168–72.

Storage condtions

Keep the Smad3 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.

Background

Mothers against decapentaplegic homolog 3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene. SMAD3 is a member of the SMAD family of proteins. It is located in 15q22.33. And it mediates the signals from the transforming growth factor beta (TGF-β) super family ligands that regulate cell proliferation, differentiation and death. Based on its essential role in TGF beta signaling pathway, SMAD3 has been related with tumor growth in cancer development.

Synonyms