MAD1 Antibody

Basic information

Name

MAD1 Antibody

size

0,1 mg

Catalog number

PB9262

Price

374 €

Details & buy    

Extended information

Target antigen

MAD1

Entrez GeneID

8379

Raised in

rabbit

Uniprot ID

Q9Y6D9

Gene Name

MAD1L1

Analyses

WB,IHC-P

French translation

anticorps

Product form

freeze-dried

Reacts with species:

human, mouse, rat

Clone

Polyclonal antibody

Clonality

Polyclonal antibody

Type of the antibody

IgG polyclonal antibody

Purification

Immunogen affinity purified.

Gene Full Name

MAD1 mitotic arrest deficient-like 1 (yeast)

Protein Name

Mitotic spindle assembly checkpoint protein MAD1

Product configuration

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Solubilization

The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml

Properties

If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Immunogen

E.coli-derived human MAD1 recombinant protein (Position: L362-A632). Human MAD1 shares 81% amino acid (aa) sequence identity with mouse MAD1.

Tips

The MAD1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.

Storage condtions

Keep the MAD1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.

Synonyms

hMAD1 antibody|HsMAD1 antibody|MAD1 antibody|MAD1 mitotic arrest deficient like 1 (yeast) antibody|MAD1-like protein 1 antibody|MAD1L1 antibody|MD1L1_HUMAN antibody|Mitotic arrest deficient 1 antibody|Mitotic arrest deficient 1-like protein 1 antibody|Mitotic checkpoint MAD1 protein homolog antibody|Mitotic spindle assembly checkpoint protein MAD1 antibody|PIG9 antibody|Tax binding protein 181 antibody|Tax-binding protein 181 antibody|TP53I9 antibody|Tumor protein p53 inducible protein 9 antibody|TXBP181 antibody

Background

Mitotic spindle assembly checkpoint protein MAD1 is a protein that in humans is encoded by the MAD1L1 gene. It is mapped to 7p22.3. MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 can function as a homodimer. It localizes to the centrosome during metaphase and to the spindle midzone and the midbody during anaphase and telophase. MAD1L1 may also play a role in cell cycle control and tumor suppression.

Related articles

1. "Entrez Gene: MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)" 2. Jin, D.-Y., Kozak, C. A., Pangilinan, F., Spencer, F., Green, E. D., Jeang, K.-T. Mitotic checkpoint locus MAD1L1 maps to human chromosome 7p22 and mouse chromosome 5. Genomics 55: 363-364, 1999. 3. Jin, D.-Y., Spencer, F., Jeang, K.-T. Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1. Cell 93: 81-91, 1998. 4. Tsukasaki, K., Miller, C. W., Greenspun, E., Eshaghian, S., Kawabata, H., Fujimoto, T., Tomonaga, M., Sawyers, C., Said, J. W., Koeffler, H. P. Mutations in the mitotic check point gene, MAD1L1, in human cancers. Oncogene 20: 3301-3305, 2001.