SMAD3 Antibody

Basic information

Name

SMAD3 Antibody

size

0.1mg

Catalog number

R32172

Price

406 €

Details & buy    

Extended information

Tested applications

WB

Recognised antigen

SMAD3

Uniprot #

P84022

Category

Antibody

French translation

anticorps

Conjugation

Unconjugated

Purity

Antigen affinity

Clone

Polyclonal antibody

Localization

Nuclear and cytoplasmic

Form

Antigen affinity purified

Clonality

Polyclonal (rabbit origin)

Recommended dilutions

Western blot: 0.1-0.5ug/ml

Host animal

Rabbit (Oryctolagus cuniculus)

Concentration

0.5mg/ml if reconstituted with 0.2ml sterile DI water

Notes

Optimal dilution of the SMAD3 antibody should be determined by the researcher.

Intented use

This SMAD3 antibodyis to be used only for research purposes and not for diagnostics..

Immunogen

Amino acids DHQMNHSMDAGSPNLSPNPMSPAHNNLDLQ of human SMAD3 were used as the immunogen for the SMAD3 antibody.

Properties

If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Species reactivity

Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.

Storage

After reconstitution, the SMAD3 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.

Description

Mothers against decapentaplegic homolog 3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene. SMAD3 is a member of the SMAD family of proteins. It is located in 15q22.33. And it mediates the signals from the transforming growth factor beta super family ligands that regulate cell proliferation, differentiation and death. Based on its essential role in TGF beta signaling pathway, SMAD3 has been related with tumor growth in cancer development.