SMAD4 Antibody

Basic information

Name

SMAD4 Antibody

size

0.08 ml

Catalog number

F50738-0.08ML

Price

199 €

Extended information

Recognised antigen

SMAD4

Uniprot #

Q13485

Category

Antibody

French translation

anticorps

Conjugation

Unconjugated

Tested applications

WB, IF, ELISA

Purity

Antigen affinity

Clone

Polyclonal antibody

Form

Antigen affinity purified

Clonality

Polyclonal (rabbit origin)

Host animal

Rabbit (Oryctolagus cuniculus)

Concentration

In 1X PBS, pH 7.4, with 0.09% sodium azide

Recommended dilutions

Western blot: 1:1000,Immunofluorescence: 1:10-1:50

Intented use

This SMAD4 antibodyis to be used only for research purposes and not for diagnostics..

Immunogen

A portion of amino acids 255-284 from the human protein was used as the immunogen for this SMAD4 antibody.

Notes

Titration of the SMAD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Properties

If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Species reactivity

Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.

Storage

Aliquot the SMAD4 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.

Description

SMAD4 is the common SMAD (co-SMAD)mediator of signal transduction by TGF-beta (transforming growth factor). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.