Smad1/5 (AF10B7) Monoclonal Antibody

Basic information

Name

Smad1/5 (AF10B7) Monoclonal Antibody

size

0.1ml

Catalog number

bsm-50347M

Price

362 €

Extended information

Tested Applications

WB

Gene ID number

4086

Modification(s)

None

Clone number

AF10B7

Swiss Prot

Q15797

Target Antigen

Smad 1/5

French translation

anticorps

Clonality

Monoclonal

Concentration

1ug per 1ul

Conjugation

Unconjugated

Recommended dilutions

WB (1.0 ug/mL)

Cross reactivity

Human, Mouse, Rat

Category

Primary Antibodies

Modification site(s)

Unmodified antibody

Purification method

Purified by Protein G.

Long name

Smad1/5 (AF10B7) Monoclonal Antibody

Also known as

Smad1/5 (AF10B7) Monoclonal Antibody

Specificity

This is a highly specific antibody against Smad 1/5.

Source

Recombinant human protein purified from E.coli (His-Smad1)

Cross reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Storage conditions

Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.

Properties

If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Synonym names

BSP1; JV41; BSP-1; JV4-1; MADH1; MADR1; Mothers against decapentaplegic homolog 1; MAD homolog 1; Mothers against DPP homolog 1; Mad-related protein 1; SMAD family member 1; SMAD 1; Smad1; hSMAD1; Transforming growth factor-beta-signaling protein 1

About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

Background of the target antigen

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.