Smad1 + Smad5 Antibody, FITC Conjugated

Basic information

Name

Smad1 + Smad5 Antibody, FITC Conjugated

size

0.1ml

Catalog number

bs-1619R-FITC

Price

333 €

Extended information

Conjugation

FITC

Modification site

None

Crossreactivity

Human

Tested applications

IF(IHC-P)

French translation

anticorps

Modification

Unmodified

Gene ID number

4090, 4086

Clonality

Polyclonal

Immunogen_range

405-440/465

Concentration

1ug per 1ul

Excitation Emission

494nm/518nm

Target Antigen

Smad1 + Smad5

Additional conjugation

Anti-FITC Antibody

Subcellular location

Cytoplasm, Nucleus

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Purification method

This antibody was purified via Protein A.

Long name

Smad1 + Smad5 Polyclonal Antibody, FITC Conjugated

Specificity

This is a highly specific antibody against Smad1 + Smad5.

Source

KLH conjugated synthetic peptide derived from human Smad 5

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Synonyms

Mothers against decapentaplegic homolog 5; SMAD5; Mothers against decapentaplegic homolog 1; SMAD1

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

Antigen background

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.

Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.