anti-MAD2L1 Antibody
0.05 mg
49-447
180 €
4085
Human
Rabbit
Q13257
Q13257
MAD2L1
12230256
anticorps
Polyclonal
in solution
Homo sapiens
unlabelled serum
Immunoaffinity Chromatography
MAD2L1, HSMAD2, MAD2, MAD2-like protein 1
MAD2 mitotic arrest deficient-like 1 (yeast)
ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
MAD2L1 antibody was made against amino acids 3-13 from the C-Terminus of MAD2L1 (Human).
Store MAD2L1 antibody at 4 grades C or -20 grades C. As with all antibodies avoid freeze/thaw cycles.
MAD2L1 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 ug/mL.
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
MAD2L1 (also called mitotic spindle assembly checkpoint protein, MAD2A, MAD2-like 1 and HsMAD2) is a component of the mitotic spindle assembly checkpoint monitors the process of kinetochore-spindle attachment and delays the onset of anaphase when this process is not complete. MAD2L1 inhibits the activity of the anaphase-promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. This protein has a nuclear localization.
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