SMAD3 (Human) ELISA Kit

Basic information

Name

SMAD3 (Human) ELISA Kit

size

100 assays

Catalog number

K4200-100

Price

834 €

Details & buy    

Extended information

Storage condition

4°C

Species reactivity

Human

Maximum time can be stored

6 months

Shipping condition

gel pack

Category

ELISA kit

Kit's other name

SMAD3 (Human) ELISA Kit

Test

ELISA Enzyme-linked immunosorbent assays Code 90320007 SNOMED

Samples tested

Human serum, plasma, tissue homogenates, culture supernatants and other biological fluids.

Applications

Quantitative measurement of SMAD3 in serum, plasma, tissue homogenates, culture supernatants and other biological fluids.

Highlights

• Detection method: Absorbance (450 nm) • Species reactivity: Human • Application: quantitative measurement of SMAD3 in human serum, plasma, tissue homogenates, culture supernatants and other biological fluids.

Kit's benefits

Easy, convenient and time-saving method to measure the level of SMAD3 in serum, plasma, tissue homogenates, culture supernatants and other biological fluids. Detection Range: 0.625 - 40 ng/ml Sensitivity: < 0.375 ng/ml

Contents

• Microplate: 96 wells • Lyophilized Standard • Sample / Standard dilution buffer • Biotin- detection antibody (Concentrated) • Antibody dilution buffer • HRP-Streptavidin Conjugate (SABC) • SABC dilution buffer • TMB substrate • Stop Solution • Wash buffer (25X) • Plate sealers

Properties

E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Kit's description

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and migration of primary keratinocytes and by altering the TGF-mediated chemotaxis of monocytes. BioVision’s SMAD3 ELISA kit is a sandwich ELISA assay for the quantitative measurement of human SMAD3 in serum, plasma and cell culture supernatants. The density of color is proportional to the amount of SMAD3 captured from the samples.