Estimated production time
3-7 business days
Please refer to NCBI
Please refer to GenBank
Protein G purified,>95%
Polyclonals and antibodies
For research use only. Not for diagnostic procedures.
Aliquot and store at -20°C. Minimize freezing and thawing.
Recombinant human Mothers against decapentaplegic homolog 2 protein (2-467AA)
ELISA,WB,IHC,IF. Recommended dilution:WB:1:2000-1:5000,IHC:1:20-1:200,IF:1:50-1:200
If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Mothers against decapentaplegic homolog 2MAD homolog 2Mothers against DPP homolog 2,JV18-1,Mad-related protein 2,hMAD-2,SMAD family member 2,SMAD 2,Smad2,hSMAD2,SMAD2,MADH2,MADR2
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.